1. Beta-blockers or Digoxin for Atrial Fibrillation and Heart Failure? - PMC
Beta-blockers · Digoxin · Perspectives for Future...
In patients with atrial fibrillation (AF) and heart failure (HF) with or without systolic dysfunction, either rhythm control or rate control is an acceptable primary therapeutic option. If a rate control strategy is chosen, treatment with a beta-blocker ...
2. Beta-blockers or Digoxin for Atrial Fibrillation and Heart Failure?
Jan 21, 2016 · Digoxin does not improve survival but may help to obtain satisfactory rate control in combination with a beta-blocker. Digoxin may be useful in ...
In patients with atrial fibrillation (AF) and heart failure (HF) with or without systolic dysfunction, either rhythm control or rate control is an acceptable primary therapeutic
3. Digoxin - Drug cabinet - BHF
If you have atrial fibrillation, it's likely your beta blockers or calcium channel blockers will be increased to the maximum dose you can tolerate before your ...
Derived from the purple foxglove plant, Digoxin was first used to treat heart complaints 200 years ago. An expert tells us about modern uses for the drug.
4. Effect of Digoxin vs Bisoprolol for Heart Rate Control in Atrial ...
Dec 22, 2020 · Although there have been safety concerns from observational studies, digoxin is more commonly used in patients who have a greater comorbidity ...
This randomized trial compares the effect of low-dose digoxin vs bisoprolol for heart rate control on quality of life in patients aged 60 years or older with permanent atrial fibrillation and dyspnea.
5. Outcomes of digoxin vs. beta blocker in atrial fibrillation - Oxford Academic
Digoxin is often viewed as less effective compared to beta blockers, especially for controlling the ventricular rate during exertion or when there is heightened ...
AbstractAims . The safety of digoxin therapy in atrial fibrillation (AF) remains ill-defined. We aimed to evaluate the effects of digoxin over beta-blocker ther
6. Digoxin Use in Modern Medicine - U.S. Pharmacist
Feb 18, 2015 · According to current guidelines, digoxin may be used as additive therapy with beta-blockers and/or ACE inhibitors/angiotensin receptor blockers ...
US Pharm. 2015;40(2):44-48.
7. BET 4. BETA-BLOCKERS OR DIGOXIN FOR RATE CONTROL OF ...
They found that digoxin was less efficacious than metoprolol in resting heart rate reduction and less efficacious than labetalol at rate reduction during ...
Report by Martin Hossack , Medical Student Checked by Rick Body , Specialist Registrar Institution: Manchester Royal Infirmary A short-cut review was carried out to establish whether beta-blockers are better than digoxin at safely controlling heart rate in patients with atrial fibrillation. A total of 525 papers was found using the reported search. None presented any evidence to answer the clinical question. It is concluded that there is no direct evidence available to guide this decision and that expert advice should be followed. A 60-year-old man comes to the emergency department with palpitations. An ECG confirms atrial fibrillation, with a ventricular rate of 140. He tells you he has been experiencing palpitations for 4 days. There are no signs of haemodynamic instability and you …
8. Beta Blockers and Digoxin in Atrial fibrillation – Back to the Future
Jul 13, 2023 · Historically, digoxin has been used for ventricular rate control in atrial fibrillation (AF) and for the treatment of heart failure with reduced ...
In his first edition of the Botany (1776), William Withering, mentioned digitalis: “It is certainly a very active medicine and merits more attention than modern practice bestows upon it”.1 Subsequently, in An Account of the Foxglove (1787), he described the effects of digitalis and noted: “After all, in spite of opinion, prejudice, or error, Time will fix the real value upon this discovery, and determine whether I have imposed upon myself and others, or contributed to the benefit of science and mankind”.
9. Role of Carvedilol and Digoxin in Heart Failure - AAFP
Jul 15, 2004 · In addition, beta blockers have been shown to improve ventricular rate control in atrial fibrillation alone or in combination with digoxin.
In the treatment of heart failure and atrial fibrillation, digoxin has been a longstanding option. It is standard therapy in patients with heart failure and atrial fibrillation, but it is inadequate at rate control in these patients during exercise or times of increased sympathetic tone. Multiple studies have shown the benefit of beta-blocker therapy in the treatment of patients with heart failure. In addition, beta blockers have been shown to improve ventricular rate control in atrial fibrillation alone or in combination with digoxin. Despite these studies, no information demonstrates that beta blockers alone or in combination with digoxin improve outcomes in patients with heart failure and persistent atrial fibrillation. Khand and associates evaluated the use of digoxin, carvedilol, and their combination in the treatment of patients with heart failure and persistent atrial fibrillation.
10. [PDF] Beta blockers, digoxin or both following an incident diagnosis of ...
May 18, 2023 · charged on digoxin alone or the combination of digoxin and a beta blocker were not associated with an increase in.
11. Digoxin | Learn the Heart - Healio
Digoxin does have a class IIa indication to control heart rates in atrial fibrillation when used in conjunction with a beta-blocker or non-dihydropyridine ...
Digoxin, originally derived from the foxglove flower, blocks the sodium/potassium ATPase pump. The mechanism by which this decreases AV conduction is not clear however is perhaps due to increased vagal tone.
12. Digoxin Could Sub for Beta-Blockers in Certain AFib Patients
Dec 28, 2020 · Low-dose digoxin seems to be a viable alternative to beta-blockers (β-blockers) to safely achieve heart rate control in patients with permanent ...
Low-dose digoxin may be useful to consider as second-line agent, experts suggest Low-dose digoxin seems to be a viable alternative to beta-blockers...
13. Atrial fibrillation medications | Royal Brompton & Harefield hospitals
Beta-blockers (bisoprolol, atenolol, carvedilol) · calcium channel blockers (diltiazem/verapamil) · amiodarone · flecainide · digoxin · dronedarone.
Antiarrhythmic medications work by helping to stabilise electrical impulses within the heart.
14. Digoxin vs Metoprolol Comparison - Drugs.com
Metoprolol is a selective beta-blocker at dosages usually prescribed to lower blood pressure or relieve the symptoms of angina. Two different salts are ...
Compare Digoxin vs Metoprolol head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
15. Calcium-Channel Blocker, Beta Blocker, and Digoxin Toxicity ...
Sep 15, 2020 · While relatively uncommon, an overdose of calcium channel blockers, beta blockers, or digoxin can result in significant morbidity and mortality, ...
Overview of emergency department management of calcium-channel blocker overdose, beta blocker overdose, and digoxin toxicity, and focuses on the caveats of treatment for each
16. Is Digoxin Still Useful in Heart Disease? - Verywell Health
May 25, 2021 · However, beta-blockers and calcium channel blockers, now commonly used to treat atrial fibrillation, are more effective for controlling symptoms ...
While potentially dangerous toxicity remains an issue, digoxin is still a reasonable option for some people with heart failure or atrial fibrillation.
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17. Digoxin a 'Viable Alternative' in AF With HF: RATE-AF Published
Dec 23, 2020 · A randomized trial shows no significant difference in the primary endpoint of quality of life at 6 months between treatment with digoxin vs ...
Researchers found no difference in quality of life between digoxin and bisoprolol in patients with AF and HF, but some secondary endpoints favored digoxin, and adverse events were less frequent.
18. Comparison of beta blocker and digoxin alone and in ... - Europe PMC
In patients with atrial fibrillation (AF) and heart failure (HF), beta blockers and digoxin reduce the ventricular rate, but controversy exists concerning ...
Europe PMC is an archive of life sciences journal literature.
19. Are beta-blockers superior and safer to digoxin for rate control ... - BestBets
Jul 7, 2008 · They found that digoxin was less efficacious than metoprolol in resting heart rate reduction and less efficacious than labetalol at rate ...
In [patients presenting to the Emergency Department with atrial fibrillation requiring rate limitation] are [beta blockers superior in efficacy and safety to digoxin] in [achieving rate control]?
20. Digoxin: a medicine to treat heart problems - NHS
NHS medicines information on digoxin – what it's used for, side effects, dosage and who can take it.
21. Latest trial led by Birmingham Professor shows digoxin is effective ...
Jan 31, 2021 · Beta-blockers have long been the drug of choice for controlling rapid heart rates in patients with atrial fibrillation (AF), but a clinical ...
A clinical trial has shown that digoxin has the same effect on physical wellbeing as beta-blockers when treating patients with permanent at
